Iowa State is coming off a close win versus Texas and is bowl eligible again. Opening line for ISU was 25+. The spread has come down a smidge to 24.5-25 based on the source. KU needs to keep mistakes to a minimum and try to get off to a fast start to have a chance. My prediction is for a closer game than the bookmakers are predicting with each team scoring range as 21-27 for KU and 29-36 for ISU.